Not able access the CD drive or DVD Drive

After you remove a program from your computer, you can no longer access the CD drive or the DVD drive successfully. The CD drive or the DVD drive does not appear. Or, you receive an error message when you try to access the drive. One of the methods requires that you manually modify the Windows registry to remove the UpperFilters registry entry and the LowerFilters registry entry. You must restart the computer after you follow the steps in this article.

To delete upperfilter & lowerfilter
Step 1: Start Registry Editor
Click Start >> click Run >> type regedit >> click OK. Registry Editor starts.

Step 2: Delete the UpperFilters // LowerFilters registry entry
In Registry Editor, expand My Computer >> HKEY_LOCAL_MACHINE >> SYSTEM >> CurrentControlSet >> Control >> Class.
Under Class, click {4D36E965-E325-11CE-BFC1-08002BE10318}.
In the right pane (topic area), click UpperFilters // LowerFilters

[Note:- An LowerFilters.bak registry entry may also appear. To delete the UpperFilters.bak // LowerFilters registry entry, you must click UpperFilters // LowerFilters and not LowerFilters.bak]

On the Edit menu [ Right Click ] click Delete >> When you receive the following message, click Yes to confirm the deletion of the UpperFilters // LowerFilters registry entry:
Are you sure you want to delete this value?
Exit Registry Editor.

and restart the computer

Also you can check the website mentioned below

http://support.microsoft.com/kb/314060